"Let science step out of the laboratory, let brightness enter millions of households" - Using education as a bridge to promote technological inclusiveness.

We always believe that education is not only a tool for knowledge spreading, but also a key bridge to promote technological inclusiveness and bring science out of the laboratory and into households. Based on the characteristics and needs of different age groups, we have carefully designed a series of interesting and interactive science popularization activities, aiming to break the "ivory tower" of science and allow everyone to gain an insight into science.

Enlightenment and care

For children and the elderly, we plan to carry out a series of fun and popular science activities based on the surrounding community to help them understand complex scientific concepts in a relaxed atmosphere.

A fun experiment will be one of the core highlights of the event. For example, in "Protein Aggregation in Milk" The experiment visually demonstrates the phenomenon of protein aggregation through a simple operation - using vinegar to coagulate milk. This is not only a fun experiment, but also can analogize the denaturation mechanism of lens proteins in cataracts, helping participants understand abstract biological principles in action. In addition, we designed the "Cataract Perspective Experience" session, which simulates blurred vision through atomized lenses or combines virtual reality (VR) technology to allow participants to immerse themselves in the visual impairment of cataract patients. The use of VR equipment will be adjusted flexibly according to the budget, and we plan to contact the teachers of the relevant laboratories ( 1) to explore the feasibility of borrowing equipment to ensure the efficient use of resources. These activities will be carried out in Zhejiang University Tianhong Kindergarten Shuiyue Park in Xihu District, Hangzhou City, and nearby neighbourhoods. The site is selected based on actual cooperation intention expectations and geographical convenience.

In order to let children experience the fun of science in the game, we have specially designed puzzle games for primary students. The game form is innovatively based on the classic logic dog panel, focusing on the formation mechanism of cataracts and the drug clearance process design tasks, helping children cultivate scientific thinking in a relaxed and pleasant atmosphere.

Scientific exploration

For high school students with a certain biological foundation, we plan to cooperate with schools such as Xuejun Middle School and Hangzhou No.2 Middle School to offer a series of open courses. These courses will cover the basic knowledge of synthetic biology, including cutting-edge fields such as gene editing technology and the application of engineering bacteria, helping students broaden their scientific horizons. In the course, we will also introduce the team's research projects, stimulate students' participation enthusiasm through prize-winning Q&A sessions, and consolidate the learning effect.

In addition, we have carefully designed a card game with "Cataract Pathogenesis and Treatment" as the core. The game includes character cards and strategy cards, such as RNF114 protein and CRYAA mutant, while strategy cards cover key concepts such as targeted delivery and ubiquitination markers. Through this interactive form, students can not only deepen their understanding of disease mechanisms, but also exercise their logical thinking and scientific reasoning abilities in game strategy.

Science communication

For adults and college students, we will expand the coverage and influence of popular science through popular science lectures and online publicity.

Firstly, we plan to launch a short video series, such as "3 Minutes to Understand New Cataract Therapy", which analyzes the mechanism of RNF114 in cataract treatment through vivid animation, helping the audience to obtain professional and accurate scientific information in a short time.

Secondly, we plan to hold an expert interview activity, inviting experts from the School of Medicine of Zhejiang University to interpret the clinical prospects of non-surgical treatment of cataracts. The interview format can be flexibly adjusted according to the needs, which can be either online LIVE, recorded videos or offline lectures to enhance interaction and communication with the audience. Currently, we have listed the list of potential cooperating experts (Attachment 1) to ensure the professionalism and authority of the lecture content.

At the same time, we will hold a science popularization exhibition, showcasing dynamic demonstrations of contact lens drug delivery systems, combined with animations and physical models for easy-to-understand explanations. In addition, we will also produce promotional brochures to facilitate visitors to obtain science popularization information at any time. The exhibition location covers densely populated areas such as the Basic Library of Zhejiang University, the main building, and the front of the East District cafeteria. It will also be exhibited in surrounding community activity centers to cover a wider audience.

Multi-language support

In order to expand the coverage of popular science, we are committed to achieving multilingual support, ensuring that people from different language backgrounds have equal access to scientific knowledge. All educational materials (including manuals, video subtitles, etc.) will be provided in both Chinese and English versions for the convenience of international students and expatriates.

In addition, if conditions permit, we also plan to cooperate with for Xinjiang and Tibet to produce Tibetan and Uyghur versions of Promotion Videos, further promote the popularization of popular science resources in ethnic minority areas, and truly achieve barrier-free spread of science education.

Evaluation and iteration

Science communication is not only the output of knowledge, but also requires effective feedback mechanisms to ensure the effectiveness of communication. To this end, we have developed a systematic evaluation and iteration mechanism to comprehensively measure the effectiveness of activities in a quantitative and qualitative way.

In terms of quantitative evaluation, we have set clear target indicators, such as the number of participants in the activity needs to hit 1000, and evaluate the effect of knowledge popularization through cataract knowledge test (comparison before and after the activity), striving to achieve a 30% increase in knowledge mastery rate. We will also use one-way ANOVA to conduct further analysis. The test questions will focus on daily scenarios and common knowledge, avoid being too obscure, and ensure that participants are easy to understand and answer.